Wet brain syndrome, also referred to as Wernicke-Korsakoff syndrome, is a brain disorder due to vitamin B1 deficiency. This happens all too often among individuals who have an alcohol problem as alcohol use disorder causes a lack of vitamin B1. In addition, wet brain happens when two different conditions, Wernicke encephalopathy, and Korsakoff syndrome, occur concurrently. Both of these problems are due to brain damage caused by a lack of vitamin B1.