Bilastine: Uses, Interactions, and Mechanism of Action

What is Bilastine?
Bilastine is a second-generation H1-antihistamine used to treat allergic rhinitis (both seasonal and perennial) and chronic idiopathic urticaria. It is known for its selectivity, long duration of action, and lack of sedation, making it a preferred choice in daily allergy management.
Uses of Bilastine
Bilastine is indicated for the relief of symptoms associated with:
1. Allergic Rhinitis
Sneezing
Nasal congestion
Runny nose
Itchy eyes and nose
2. Chronic Idiopathic Urticaria
Persistent hives
Redness
Itching and swelling
Key Benefits:
Works within 1 hour of administration
Provides relief for up to 24 hours
Non-sedating and does not impair driving or cognitive function
Dosing and Administration
Adults and children ≥12 years: 20 mg once daily
Should be taken on an empty stomach
Not recommended in patients with severe renal impairment if co-administered with P-gp inhibitors
Safety and Side Effects
Bilastine is generally well-tolerated. Common side effects (typically mild) may include:
Headache
Dizziness
Abdominal pain
Drowsiness (rare)
It does not significantly affect the heart (no QT prolongation), liver, or kidneys in healthy individuals.
Conclusion
Bilastine offers effective allergy relief with minimal side effects, positioning itself as a reliable option for patients seeking a non-drowsy antihistamine. Its once-daily dosing, rapid onset, and long-lasting action make it particularly convenient for individuals managing chronic allergic conditions.
Whether you're dealing with seasonal allergies or chronic hives, Bilastine is a modern antihistamine worth considering — provided it’s taken correctly and with awareness of potential interactions.
URL: For more information, visit Vasista Pharma: Bilastine: Uses, Interactions, and Mechanism of Action